Job Summary (Primary function)
As a Sr. Research Investigator, you will be a key contributor to the Immunology Group’s efforts to better understand the complex the role of the innate immune system in modulating autoimmune disease. To succeed in this position will require a strong background in innate immunology, performing advanced immune-based assays, and a strong desire to translate scientific discoveries into novel therapeutic treatments. The successful candidate will work within a multidisciplinary team.
Essential Functions of the Job (Key responsibilities):
Design, execute, and analyze complex immunological experiments focused on innate immune mechanisms in autoimmune diseases, including:
Develop ex vivo primary cell functional assays using innate immune cells
Analyze and interpret complex data sets, present findings to internal and external stakeholders, and contribute to scientific publications.
Maintain accurate and detailed records of experimental procedures and results.
Take on increasing leadership responsibilities, including project leadership and scientific strategy development.
Qualifications (Minimal acceptable level of education, work experience, and competency)
Ph.D. in Immunology or a related field, with a focus on innate immunity or autoimmunity.
Minimum of 2-3 years of postdoctoral or industry experience in immunology, preferably with a focus on autoimmune diseases.
Extensive hands-on experience with advanced immune-based assays, including flow cytometry, CyTOF, multiplex assays, and RNA sequencing, with a focus on innate immune cell analysis.
Strong understanding of innate immune cell biology, signaling pathways, and their role in autoimmune pathogenesis.
Experience with cell culture and primary cell isolation techniques, particularly related to innate immune cells
Experience with preclinical in vivo models of autoimmune disease.
Individuals with experience in GVHD and/ or lung disease models and/ or myeloid cell research are strongly encouraged to apply.
Proficiency in data analysis software (e.g., FlowJo, Prism, R).
Excellent communication, presentation, and interpersonal skills.
Strong problem-solving and critical thinking skills.
Experience with writing scientific publications.
Preferred Skills:
Knowledge of bioinformatics and data analysis tools
- Experience using software to visualize multi-dimensional flow and CyTOF data (e.g., t-SNE, UMAP, viSNE).
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
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During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process .
