Job Summary (Primary function)
The successful applicant will assume an integral role leadingin silicovitroandvivoantibody discovery workflows within silico
Job Responsibilities
- Contribute to the identification and optimization of lead compounds by leveraging artificial intelligence and/or machine learning strategies forin silicosequence design and optimization
- Manage Rosetta-based molecular modeling projects to support lead molecule refinement
- Proactively identify and deploy open-source models and develop in-house ML based models to facilitate Antibody discovery and optimization.
- Leverage next-generation antibody sequencing data together with wet-lab experimental data to empower in silico sequence design
- Maintain detailed and up-to-date electronic lab notebook
- Data analysis and presentation to program teams
- Work collaboratively under aggressive timelines
Minimum Requirements
- PhD with 1-3 years’ of relevant experience, industry experience preferred
- Strong background in antibody biology/engineering and/or B cell immunology
- Strong computational background with experience in programming languages such as Python, R etc.
- Proficient in the application of in silico methods for antibody discovery and sequence optimization
- Proficient in identifying deploying ML based models to leverage in house experimental data to support Antibody discovery programs.
- Hands on experience in single B cell screening technologies preferred.
- Experience with next-generation sequencing approaches and antibody sequence analysis a plus
Excellent organization and communication skills
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
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During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process .
