Teva Senior Research Scientist Antibody Generation 

Australia, Western Australia 

68394816

This is a Hands-on laboratory-based role within the antibody generation team requiring capabilities and responsibilities including:

• Conduct research and development (planning, execution, and interpretation) on therapeutic antibody discovery projects.
• General molecular biology (e.g. PCR, DNA purification and analysis, vector design, DNA cloning)
• DNA and protein sequence analysis
• Design and execution of antibody discovery and optimization campaigns in-house and in collaboration with partners and CROs.
• Design of semisynthetic display libraries
• Generation and screening of immune libraries
• Design of different formats of antibodies (scFv, Fabs, multispecifics)
• Optimise antibody attributes for potency, developability and immunogenicity!
• Development and use of biochemical assays for screening antibody and recombinant protein function (e.g. SPR, ELISA and other immunoassays or screening technologies)
• Use automation to support antibody production, purification, and screening!
• Identify and implement new antibody optimisation technologies and other platform improvements as the need arises!
• Expertise in collecting, analysing, interpreting data, and making recommendations to key stakeholders through clear and concise oral and written communication.
• Record keeping and maintaining detailed, accurate electronic laboratory notebooks that support data driven decision making, generation of IND submission quality reports.
• Efficient collaboration wit
• Mentoring of peers and supporting the development of junior colleagues.
• Provide regular updates in the form of presentation and reports to the discovery project team.
• Managing projects with contract research organisations
• Presenting work regularly at internal meetings
• Work hand in hand with other teams including cell-based assays, protein generation, CMC, and pre-clinical pharmacology to ensure project goals and timelines are met.
• Compliance with all employee health and safety, PC2 and gene technology guidelines including adherence to TEVA policies and procedures.
• Corporate citizenship, including serving on in-house committees.

• PhD with minimum 4 years’ experience in life sciences
• Qualifications in Molecular Biology, Protein Engineering, Immunology, or a related field
• Strong molecular biology skills
• Proven expertise in immunogenicity assessment methodologies, including in vitro and in silico approaches.
• Previous experience in industry-based R&D highly regarded.
• An understanding of the drug discovery and development process related to therapeutic antibodies.
• Knowledge of immune repertoire and antibody structure/function is desirable.
• Proven track record of adopting new technologies or experimentation – promotes continuous improvement.
• Ability to communicate effectively (both written and verbal) is required.
• Experience managing staff is highly desirable.
• An active interest in therapeutic drug discovery and development
• Ability to organise and report study data from internal and external sources.
• Excellent interpersonal skills, a can-do attitude and driven by succeeding as a team.
• Excellent adaptability and problem-solving skills.
• Ability to work in independently and within cross-functional teams, with a strong focus on engagement and influence of team members.
• Well organised, attention to detail and able to coordinate multiple activities simultaneously.

• Work with a motivated team of scientists in state-of-the-art laboratories.
• Generous leave, health, and wellbeing benefits
• Commitment to ongoing personal & professional growth via a blend of learning opportunities
• Parking available at our Macquarie Park site
• Opportunity to join a leading global organisation with a network of 37,000 employees operating in 60 markets, with 25 R&D sites

Associate Director -Biologics

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