MSD Sr Scientist Molecular Discovery 

United Kingdom, England, London 

410939431

Job Description

Role Overview:

You will be part of a new multi-disciplinary team generating antibodies to support new drug candidate discovery and development. As a laboratory based scientist, you will be responsible for key aspects in the identification, expression, purification, engineering and characterisation of pre-clinical candidate molecules. The role is a key interface with immunology, neuroscience and other functions across our company, as well as with external academic and industrial partners.

What you will need to be successful in this role:

• Exceptional wet-lab and excellent communication skills.

• A high level of independent motivation and a strong team work ethic.

• Ability to deliver to tight timelines and work effectively across departments and multi-disciplinary teams.

• Passion for innovation and problem-solving.

• Good organisational, time management and record keeping skills.

• Ability to adapt to changing priorities.

• We recognise that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviours in working with a diverse group of scientists to drive our core mission.

Responsibilities:

• Unique opportunity to help build and shape the new Discovery Biologics laboratory.

• Proactively drive antibody projects from the laboratory.

• Design, plan and execute experiments and analyse data independently, demonstrating scientific rigor and critical thinking.

• Document protocols and data in electronic laboratory notebooks and internal biological registration system.

• Report and disseminate data to project teams.

• Present experimental data at cross-functional meetings.

Required Experience:

• PhD in Biochemistry / Immunology / Neuroscience / Molecular Biology (or related field), or a M.Sc. and a minimum of 5+ years industry experience, or a B.Sc. with 8+ years of industry experience.
• Excellent communication skills and collaborative mindset with ability to work and share knowledge across disciplines and departments.

Preferred experience:

• Relevant pharmaceutical industry experience highly preferred.

Working knowledge in some of the following areas:

• Antibodystructure/function/novelformats.
• Practical experience with analytical assays for characterisation, and biophysical understanding of proteins/antibodies (e.g. LC/MS, SPR).
• Cell culture - protein expression and purification (e.g. Affinity chromatography, IEX, HIC, SEC, AKTA).
• Molecular biology (e.g. PCR, cloning and mutagenesis).
• Antibody sequence optimisation and engineering.
• Outsourcing and working with CROs.
• High-dimensionalflow cytometry and FACS-based immunophenotyping (both panel design and downstream data analysis).
• Protein design/engineering (structure-based, AI-guided).
• Operating automation (e.g. liquid handling).

20th January 2025

Current Contingent Workers apply

Not Applicable

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